毛细支气管炎患儿血清维生素D及免疫球蛋白水平的意义

Significance of Serum Vitamin D and Immunoglobulin Level of Children with Bronchiolitis

目的观察对毛细支气管炎患儿使用维生素D后的效果及对免疫球蛋白水平的影响。方法选取该院毛细支气管炎患儿94例(2016年10月—2017年3月期间),将其依据单双号编号分组原则,分为对照组(常规对症治疗)、观察组(再使用维生素D),各47例,对比两组毛细支气管炎患儿检测的血清25-(OH)D_3情况和4项免疫球蛋白情况。结果观察组毛细支气管炎患儿的血清25-(OH)D_3数据为(74.06±15.91)nmol/L,优于对照组的情况(P<0.05);观察组的4项免疫球蛋白指标——IgA(0.46±0.10)g/L,IgM(1.05±0.30)g/L,IgG(7.49±4.26)g/L,IgE(113±27.00)×10~3IU/L,均优于对照组(P<0.05)。结论给毛细支气管炎患儿加服维生素D后能够在短期内明显提高其体内血清25-(OH)D_3水平,同时对患儿机体当中的免疫球蛋白水平有较好的控制和调节效果。

Objective To observe the effect of serum vitamin D and immunoglobulin level of children with bronchiolitis. Methods 94 cases of children with bronchiolitis in our hospital from October 2016 to March 2017 were selected and divided into two groups according to the admission order with 47 cases in each, the control group adopted the routine symptomatic treatment, while the observation group adopted the vitamin D, and the serum 25 -（OH） D3 and four im-munoglobulin situations were compared between the two groups. Results The serum 25-（OH） D3 was（74.06±15.91）nmol/ L, which was better than that in the control group（ P〈0.05）, and the four immunoglobulin indicators of IgA（0.46±0.10）g/ L, IgM（1.05±0.30）g/ L, IgG（7.49±4.26）g/ L, IgE（113±27.00）x103 IU/L were better than those in the control group（ P〈0.05）. Conclusion Adding the vitamin D for children with bronchiolitis can obviously improve the serum 25- OH） D3 level in a short time, at the same time, it has a better control and adjustment effect on the immunoglobulin level in the organism of children.