摘要
目的观察低钙透析液联合活性维生素D及醋酸钙治疗血液透析患者继发性甲亢疗效。方法收集2015年7月—2016年6月兖矿集团总医院血液净化科35例慢性肾功能衰竭维持性血液透析患者,采用浓度为1.25mmol/L低钙透析液,联合活性维生素D冲击治疗及口服醋酸钙片应用3、6个月后观察血清钙、磷、钙磷乘积、血清全段甲状旁腺激素的变化。将不同时间点测定的结果进行分组,治疗开始时测定结果作为A组、接收治疗3月测定结果作为B组、接受治疗6月测定结果作为C组。结果 35例患者治疗后血Ca、P、Ca X P、i PTH分别为(8.65±0.57)mg/d L、(45.11±6.95)mg/d L、(45.11±6.95)mg2/d L2、(569.77±181.74)pg/m L;11例患者自觉皮肤瘙痒较前减轻,2例患者骨痛不适感有所缓解,5例患者关节痛略减轻;1例出现低血压伴有眩晕感。结论低钙透析液联合活性维生素D及醋酸钙治疗血液透析患者继发性甲亢疗效显著,安全性高。
Objective To observe the curative effect of low dialysate calcium and activated vitamin D and calcium acetate in treatment of secondary hyperparathyroidism of patients with hematodialysis. Methods 35 cases of patients with chronic renal failure maintenance hemodialysis in our hospital from July 2015 to June 2016 were collected and the1.25mmol/L low dialysate calcium was used and the activated vitamin D impulse therapy and oral administration of calcium acetate tablets were applied for three months, after six months, the changes of serum calcium, phosphorus, calcium phosphorus product, intact parathyroid hormone were observed.results at the beginning of treatment were taken as the A group. The results of the treatment in three months were taken as the B group, and treated in six months. The results of the test were used as the C group. Results After treatment, the blood Ca, P,Ca X P,i P TH of 35 cases of patients were respectively(8.65±0.57)mg/d L,(45.11±6.95)mg/d L,(45.11±6.95)m2/d L2,(569.77±181.74)pg/m L, and the skin itch of 11 cases was relieved and the bone pain discomfort of 2 cases was relieved and the joint pain of 5 cases was slightly relieved and 1 case was with hypotension and dizziness. Conclusion The curative effect of low dialysate calcium and activated vitamin D and calcium acetate in treatment of secondary hyperparathyroidism of patients with hematodialysis is obvious with high safety.
出处
《系统医学》
2017年第10期47-49,共3页
Systems Medicine
