幼儿急疹合并热性惊厥发作的危险因素分析

Analysis of Risk Factors of Exanthema Subitum and Febrile Seizures

目的调查并分析幼儿急疹合并热性惊厥发作的危险因素。方法对2016年1—12月该院收治的960例急疹患儿的临床资料进行回顾性分析,以患儿是否合并热性惊厥为依据将其分为两组,即合并热性惊厥组(n=154)和未合并热性惊厥组(n=806),对比两组患儿的性别、年龄、最高体温、发热持续时间、出疹持续时间、家族史等基本资料,单因素分析差异有统计学意义(P<0.05),则采用Logistic回归分析法进行分析,总结出惊厥发作的相关危险因素。结果该院共收诊960例急疹患儿,其中154例患儿发生惊厥,在所有发热患儿中所占比例为16.04%;在年龄和家族史的比较上,合并热性惊厥组患儿年龄<12个月以及存在家族史所占比例明显高于未合并热性惊厥组患儿,组间对比差异有统计学意义(P<0.05);经Logistic回归分析,年龄<12个月以及存在家族史与急疹合并热性惊厥发作具有相关性(P<0.05)。结论年龄<12个月以及存在家族史是急疹合并热性惊厥发作的独立危险因素,在临床上应给予有效预防,以降低急疹合并热性惊厥的发生率。

Objective To investigate the risk factors of exanthema subitum and febrile seizures. Methods 960 cases of children with exanthema subitum admitted and treated in our hospital from January 2016 to December 2016 were selected and divided into two groups, one group was the patients with exanthema subitum and febrile seizures(n=154),and the other group was the patients with exanthema subitum without febrile seizures(n=806), and the basic data of gender, age, highest temperature, fever duration, rash duration and family history were compared between the two groups and the related risk factors were summarized by the Logistic regression analysis. Results Of 960 cases of exanthema subitum children, there were 154 cases with seizures, accounting for 16.04% in total, and the ratio of children with exanthema subitum and febrile seizures whose age <12 months and with family history was obviously higher than that of children with exanthema subitum without febrile seizures, and the difference between groups was obvious(P<0.05),and the Logistic regression analysis showed that the age <12 moths had a correlation with the family history and exanthema subitum and febrile seizures(P<0.05). Conclusion The age <12 months and family history are the independent risk factors of exanthema subitum and febrile seizures, and we should conduct the effective prevention in clinic in order to reduce the incidence rate of exanthema subitum and febrile seizures.