钙通道阻滞剂对治疗老年高血压临床疗效探讨

Analysis of Clinical Effect of Calcium Channel Blocker on the Treatment of Senile Hypertension

目的观察钙通道阻滞剂对治疗老年高血压临床疗效。方法收取该院140例老年高血压患者,收取时间在2016年7月—2017年3月,并将老年高血压患者分为两组,对照组(70例患者实施叶酸治疗),观察组(70例患者实施拜新同治疗),探讨两组老年高血压患者的治疗效果。结果观察组患者发生头痛有1例、颜面潮红有2例、下肢水肿有3例、不良反应发生率为8.57%低于对照组(P<0.05),观察组老年患者BUM(5.60±1.62)ng/mL、TC(6.02±1.27)ng/mL、TG(1.32±0.90)ng/mL、GLU指标(5.78±1.01)ng/mL优于对照组(P<0.05),观察组老年高血压患者治疗后的心脑血管病死亡率2.86%低于对照组(P<0.05)。结论钙通道阻滞剂对治疗老年高血压患者具有显著治疗效果,能缓解不良反应,改善BUM、TC、TG、GLU指标以及降低心脑血管病死亡率,值得应用。

Objective This paper tries to observe the effect of calcium channel blockers on treatment of senile hypertension patients. Methods 140 elderly patients with hypertension treated in this hospital from July 2016 to March 2017 were selected and divided into two groups, with 70 patients in each group. The control group received folic acid treatment, the observation group received adalat treatment, and the clinical effect of both groups was analyzed. Results 1case of headache, 2 case of facial flushing, 3 case of lower limb edema occurred, the incidence rate of adverse reaction was 8.57%, lower than that of the control group（P0.05）, BUM of the observation group was（5.60±1.62）ng/mL, TC of（6.02±1.27）ng/mL, TG was（1.32±0.90）ng/mL, GLU index was（5.78±1.01）ng/mL, better than the control group（P0.05）,cardiovascular disease mortality of the observation group after treatment was 2.86%, lower than that of the control group（P0.05）. Conclusion Calcium channel blockers have significant therapeutic effects on elderly patients with hypertension; it can alleviate their adverse reactions, improve BUM, TC, TG, GLU indicators, and reduce the mortality of cardiovascular and cerebrovascular diseases. Therefore, it is worth application