中老年居民饮绿茶习惯与骨密度相关性研究

Association of habitual green tea consumption with bone mineral density among the middle-aged and the elderly in Ningbo

目的通过对城区中老年人群调查和骨密度(bone mineral density,BMD)检测,了解饮绿茶与骨密度及骨量异常关联性。方法对2013年7月至2015年6月到东柳街道社区卫生服务中心体检的40~89岁居民进行调查并检测BMD。结果本研究共调查检测399例对象,其中男性67例(16.79%),女性332例(83.21%),饮绿茶48例(12.03%),不饮绿茶351例(87.97%)。骨量异常比例饮绿茶组低于不饮绿茶组。简单线性回归分析中饮绿茶与女性股骨颈及腰椎BMD均存在关联,并且有剂量效应关系。多元线性回归分析中饮绿茶在女性中与腰椎BMD存在剂量效应关系(β=0.127,P=0.022)。在绝经女性中饮绿茶与股骨颈BMD(β=0.111,P=0.023)及腰椎BMD(β=0.127,P=0.019)均存在剂量效应关系。单因素logistic回归分析中,饮绿茶对象发生骨量异常的风险更低,OR=0.42(95%CI:0.20~0.87),关联主要存在女性中,OR=0.34(95%CI:0.12~0.92),并且女性中存在剂量效应关系。多因素logistic回归分析中,未发现饮绿茶与骨量异常存在关联。结论饮较多绿茶与女性腰椎BMD呈正相关,与绝经女性股骨颈BMD也呈正相关。

Objective To discuss the association between habitual green tea drinking and bone mineral density（BMD）among the middle-aged and the elderly in Ningbo. Methods A questionnaire survey was conducted and BMD was measured among residents aged 40-89 years who received physical examination in the center from July 2013 to June 2015. Results A total of 399 subjects were enrolled in this study,including 67 men（16.79%）and 332women（83.21%）,48subjects（12.03%）had the habit of drinking green tea and 351subjects（87.97%）did not have.The percentage of those with abnormal BMD was lower among green tea drinkers.Simple linear regression analysis showed that green tea consumption was associated with female BMD of femoral neck and lumbar vertebra at dose-related response.Multiple linear regression analysis also revealed an obvious dose-related response between green tea consumption and BMD of lumber vertebra（β=0.127,P=0.022）among women,as well as BMD of femoral neck BMD（β=0.111,P=0.023）and lumber vertebra（β=0.127,P=0.019）among women of postmenopause.Single-factor logistic regression analysis showed that green tea drinkers were less likely to have abnormal BMD（OR=0.42,95%CI：0.20-0.87）,especially women（OR=0.34,95%CI：0.12-0.92）,and in a dose-related manner.Multi-factor logistic regression analysis showed no significant association between green tea consumption and abnormal BMD. Conclusions Green tea consumption is positively related with female BMD of lumber vertebra,as well as BMD of femoral neck among women during menopause.