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促红细胞生成素用于化疗晚期癌症患者的疗效 被引量:1

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摘要 目的探讨重组人促红细胞生成素(r Hu EPO)用于化疗的晚期癌症患者的疗效。方法调查了30例晚期癌症患者连3次化疗的病志,其血红蛋白(HGB)疗前<110 g/L,均行r Hu EPO治疗,1周3次皮下注射,连6周。收集一般资料,血常规结果及生活质量(QOL)评分,用t检验对数据进行分析。结果 30例疗前HGB为(88.8±8.4)g/L,红细胞压积(HCT)为(23.9±3.1)%,网织红细胞百分数(RET%)为(1.15±0.07)%,QOL评分为(47.3±3.6),3周后,HGB为(94.9±7.5)g/L,HCT为(27.4±2.6)%,RET%为(1.33±0.07)%,QOL评分为(49.0±3.9),6周后,HGB为(109.8±9.1)g/L,HCT为(30.5±4.5)%,RET%为(1.85±0.08)%,QOL评分为(50.8±5.5),3次结果差异经t检验有统计学意义。疗程中,2例发生血栓,1例发热,2例血压升高。结论r Hu EPO可提高姑息化疗癌症患者的HGB及生活质量,耐受性佳。
作者 苏贺
出处 《中国医药指南》 2017年第25期160-161,共2页 Guide of China Medicine
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