自体组织封堵经指引导丝导致冠脉穿孔的安全性及有效性研究“来自一项单中心小样本回顾性研究”

Safety and efficacy of autologous tissue plugging percutaneous coronary interventional therapy(PCI) to lead to coronary perforation——a single center and small sample retrospective investigation

目的评价自体组织封堵经皮冠状动脉介入治疗(PCI)指引导丝导致冠脉穿孔的安全性及有效性研究。方法回顾性收集收治本中心PCI致冠脉穿孔患者28例,比较不同处理方法的成功率及副作用(球囊低压扩张封堵法、明胶海绵颗粒经微导管推入封堵法作为A组、自体组织封堵法为B组)。结果 (1)两组间封堵效果存有显著差异性(χ~2=8.00,P<0.05);(2)自身组织封堵组一次成功率95%,满足各类分型的封堵。结论冠脉穿孔后采用自身组织封堵具有较高封堵成功率且安全、经济。

Objective To evaluate the safety and efficacy of autologous tissue plugging percutaneous coronary interventional therapy（PCI）to lead to coronary perforation. Methods 28 patients with coronary artery perforation resulted from PCI and hospitalized in cure center were collected retrospectively. Success rate and side effects about different methods were compared. These methoed included low pressure expansion seal method,gelatin sponge particles by micro catheter leading into the block,autologous tissue block method.Results（1）There was significant difference between blocking effects in each method（P 0.05）.（2）Success rate was 95% in the self-organizing group and this method could meet the sealing of all kinds of types,P0.05. Conclusion After coronary perforation,self tissue sealing has higher sealing success rate. And it is safe and economic.