经皮椎体成形术治疗骨质疏松性椎体压缩性骨折的临床疗效分析

Clinical efficacy analysis of percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures

目的研究分析经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折(OVCF)的临床疗效。方法 116例骨质疏松性椎体压缩性骨折患者,依据治疗方法不同分为研究组(60例)与对照组(56例)。研究组患者实施PVP治疗,对照组患者实施常规保守治疗。观察比较两组患者的治疗效果。结果治疗后,研究组总有效率95.00%高于对照组的80.36%,差异具有统计学意义(P<0.05)。治疗前两组视觉模拟评分法(VAS)评分比较差异无统计学意义(P>0.05);治疗后研究组VAS评分低于对照组,差异具有统计学意义(P<0.05)。治疗前两组椎体前缘高度、后凸Cobb角比较差异均无统计学意义(P>0.05);治疗后,研究组椎体前缘高度、后凸Cobb角优于对照组,差异均具有统计学意义(P<0.05)。结论骨质疏松性椎体压缩性骨折患者实施PVP治疗,具有良好的临床效果,值得推广。

Objective To study and analyze the clinical efficacy of percutaneous vertebroplasty（PVP） in the treatment of osteoporotic vertebral compression fractures（OVCF）. Methods A total of 116 patients with osteoporotic vertebral compression fractures were divided by different treatment methods into research group（60 cases） and control group（56 cases）. The research group received PVP treatment, and the control group received conventional conservative treatment. Treatment effect in two groups was observed and compared. Results After treatment, the research group had higher total effective rate as 95.00% than 80.36% in the control group, and the difference was statistically significant（P〈0.05）. Before treatment, both groups had no statistically significant difference in visual analogue scale（VAS） score（P〉0.05）. After treatment, the research group had lower VAS score than the control group, and the difference was statistically significant（P〈0.05）. Before treatment, both groups had no statistically significant difference in vertebral anterior height and kyphosis Cobb angle（P〉0.05）. After treatment, the research group had better vertebral anterior height and kyphosis Cobb angle than the control group, and the difference was statistically significant（P〈0.05）. Conclusion PVP provides remarkable clinical effect for patients with osteoporotic vertebral compression fractures, and it is worthy of promotion.