摘要
目的探讨Gene-Xpert MTB/RIF在西藏地区结核病诊断中的应用价值。方法对974例可疑结核病患者的标本同时进行结核涂片抗酸染色镜检和Gene-Xpert MTB/RIF检测。对比两种检测结果。结果 974例检测标本中,Gene-Xpert MTB/RIF检测阳性率为12%(118/974),其中利福平敏感的标本为93例,利福平耐药的标本为25例(耐药率为21%)。抗酸染色阳性标本为15例,检测阳性率为2%。Gene-Xpert MTB/RIF检测阳性率高于抗酸染色,差异具有统计学意义(P<0.05)。结论 Gene-Xpert MTB/RIF在西藏地区结核病诊断和治疗中具有较好的临床应用价值,且方法简便、快速。
Objective To investigate the application value of Gene-Xpert and MTB/RIF in the diagnosis of tuberculosis in Tibet. Methods Specimens of 974 suspected tuberculosis patients all received acid fast staining microscopy and Gene-Xpert MTB/RIF test by tuberculosis smear, and the two test results were compared. Results Among 974 test specimens, the positive rate of Gene-Xpert MTB/RIF was 12%(118/974), including 93 rifampicinsensitive specimens and 25 rifampicin-resistant specimens(resistance rate as 21%). There were 15 Acidpositive specimens, with detection positive rate as 2%. The positive rate of Gene-Xpert MTB/RIF was higher than that of acid-fast staining, and the difference was statistically significant(P〈0.05). Conclusion Gene-Xpert MTB/RIF shows excellent clinical application value in diagnosis and treatment of tuberculosis in Tibet, and this method is simple and rapid.
作者
嘎松卓嘎
普芝
巴桑琼达
小尼玛
GASONGZHUOGA PUZHI BASANGQIONGDA et al(Department of Clinical Laboratory, People's Hospital of Tibet Autonomous Region, Lhasa 850000, Chin)
出处
《中国实用医药》
2017年第26期27-28,共2页
China Practical Medicine