摘要
目的研究注射用复方骨肽与抗炎药物的配伍稳定性,以期指导临床用药。方法本文主要研究复方骨肽与注射用头孢地嗪的稳定性,将注射用复方骨肽与注射用头孢地嗪进行配伍,静置0、2、4、6、8 h后,观察配伍液的外观,检测其PH值及含量变化,从而评价两药配伍的稳定性。结果注射用复方骨肽与头孢地嗪配伍后,在8h内配伍液外观、PH值以及含量均未见明显变化。结论临床上注射用复方骨肽与抗炎药物可以配伍使用,在配伍8h内基本稳定,建议8h内使用完毕。
Objective To study the stability of compatibility of compound ossotide and antiinflammatory drugs in orderto guide the clinical use of drugs. Methods In this study, we studied the stability of compound ossotide and Embodiment for injection. The compound ossotide and Embodiment were given for compatibility. After standing for 0, 2, 4, 6 and 8 hours, the appearance, Its PH value and content change, so as to evaluate the compatibility of the two drugs stability. Results After 8 months, the appearance, PH value and content of the compounded bone peptide and Embodiment did not change obviously. Conclusions The combination of compound ossotide and anti - inflammatory drugs can be used in clinic, and it is stable in 8 hours after compatibility. It is recommended to use it within 8 hours.
出处
《航空航天医学杂志》
2017年第8期937-940,共4页
Journal of Aerospace medicine
关键词
注射用复方骨肽
高效液相色谱法
配伍
稳定性
Compound Ossotide Injection
high performance liquid chromatography
Compatibility
The stability of