RGS16蛋白在口腔鳞状细胞癌中表达意义的初探

Significance of RGS16 protein expression in oral squamous cell carcinoma

采用免疫组织化学染色法检测RGS16蛋白在84例口腔鳞状细胞癌(OSCC)患者癌组织中的表达情况,分析其与口腔鳞状细胞癌临床病理特征之间的关系。结果表明:78例RGS16蛋白表达阳性,其表达强度与口腔鳞状细胞癌的临床分期有关(P<0.05),与患者的年龄、性别、淋巴结转移以及分化程度无明显相关性(P>0.05)。

RGS16 protein expression in 84 cases of oral squamous cell carcinoma（OSCC） was examined by immunohistochemical staining method. RGS16 protein expression was positive in 78 out of the 84 cases. The expression was associated with the clinical stage of OSCC（P 〈 0.05）, but not with patient＇s age, gender, degree of differentiation and lymph node metastasis（P 〉 0.05）.