摘要
目的建立气相色谱-质谱联用测定工作场所空气中12种乙二醇醚类化合物的方法。方法工作场所空气中的乙二醇醚用活性炭采样管采集,二氯甲烷-甲醇(15+85,V/V)溶液解吸,DB-624毛细管柱分离,气相色谱-质谱法定性定量。结果 12种乙二醇醚类化合物可完全分离,测定的线性范围、最低检出浓度、采样效率、穿透容量、解吸效率、准确度、精密度、样品稳定性均符合GBZ 210.4—2008中要求;对使用了含部分上述乙二醇醚涂料的3类场所30个样品进行测定,共检出4个阳性样品,乙二醇单甲醚、乙二醇单乙醚、乙二醇甲醚乙酸酯、乙二醇乙醚乙酸酯4种化合物,且与原料标示成分一致。结论本法可用于工作场所空气中12种乙二醇醚类化合物的监测。
Objective To establish a determination method of 12 ethylene glycol ethers in workplace air by gas chromatography-mass spectrometry. Methods The ethylene glycol ether compounds in workplace air was collected by activated carbon sampling tubes,desorbed with dichloromethane-methanol（ 15 ＋ 85,V/V） solution,separated by DB-624 capillary column,and analyzed quantitatively and qualitatively by gas chromatography-mass spectrometry. Results 12 kinds of glycol ethers were completely separated. The linear range,the lowest detection concentration,sampling efficiency,penetrating capacity,desorption efficiency,accuracy,precision,and sample stability were in accordance with GBZ 210. 4—2008 requirements; in three types of places,using paint containing some of the above-mentioned glycol ether compounds,total 30 samples were detected,4 positive samples were detected,there were 4 kinds of compounds respectively,such as 2-Methoxyethanol,2-Ethoxyethanol,2-Methoxyethyl acetate,2-ethylene acetate,which were consistent with the raw material composition. Conclusion The method can be used in the monitoring of 12 kinds of target glycol ether compounds in workplace air.
出处
《中国卫生检验杂志》
CAS
2017年第17期2452-2455,2460,共5页
Chinese Journal of Health Laboratory Technology
基金
深圳市卫生计生系统科研项目(201402119)
