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改进型高压氧治疗方案对脑梗死患者血脂及血液流变学的影响 被引量:4

The effect of improved hyperbaric oxygen therapy on blood lipids and blood rheology for cerebral infarction
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摘要 目的观察加压阶段吸氧的改进型高压氧治疗方案对脑梗死患者血脂及血液流变学的影响。方法选取2014年1月至2014年6月本院及益阳市人民医院高压氧科治疗的脑梗死患者共80例,分为观察组(40例)和对照组(40例)。观察组患者应用改进型高压氧治疗方案(加压阶段吸氧气),对照组应用常规高压氧治疗方案(加压阶段吸空气)。在治疗前和治疗四个疗程(40次)后,分别检测血脂、血液流变学指标。结果(1)两组治疗后血浆总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白(LDL—C)水平均较治疗前明显下降,高密度脂蛋白(HDL—C)水平明显升高,差异均有统计学意义(P〈0.05);治疗后观察组TC、TG和LDL—C水平明显低于对照组,HDL—C明显高于对照组,差异均有统计学意义(P〈0.05)。(2)两组治疗后血液流变学各项指标均较治疗前明显下降,差异有统计学意义(P〈0.05);治疗后观察组血液流变学各项指标明显低于对照组,差异有统计学意义(P〈0.05)。结论改进型高压氧治疗方案较传统治疗方案可显著改善脑梗死患者血脂、血液流变学指标。 Objective To investigate the effect of improved hyperbaric oxygen therapy on blood lip- ids and blood theology for cerebral infarction. Methods A total of 80 patients with cerebral infarction was chosen in Yiyang Central Hospital and Yiyang People's Hospital from January 2014 to June 2014. Among them, 40 cases were chosen as experimental group, and the other 40 cases as control group. All the patients received 4-course hyperbaric oxygen treatment. The blood lipids and blood rheology were observed before and after therapy. Results (1) As for two groups, total cholesterol (TC), triglyceride (TG) and low density lipoprotein-cholesterol (LDL-C) levels were decreased obviously, while high density lipoprotein-choles- terol (HDL-C) level rose obviously after 4-course hyperbaric oxygen treatment, with statistically significant differences ( P 〈 0. 05 ). Although the same results were observed in experimental group after treatment compared to the control group after treatment (P 〈 0. 05 ). (2) The whole index for blood rheology of two groups decreased significantly after the treatment ( P 〈 0. 05 ). In addition, there was a statistically signifi- cant decline in hemorheology index for experimental group after treatment compared to the control group after treatment (P 〈 0. 05). Conclusions Compared to the traditional treatment programs, the improved hyperbaric oxygen therapy can significantly improve the index for blood lipids and blood rheology.
作者 李佳 刘敏
出处 《中国医师杂志》 CAS 2017年第9期1374-1377,共4页 Journal of Chinese Physician
关键词 高压氧 脑梗死/治疗/代谢 脂类代谢 血液流变学 Hyperbaric oxygenation Brain infarction/TH/ME Lipid metabolism Hemorheology
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