凝血酶原时间延长的代偿期肝炎肝硬化患者症状分布特点研究

Symptoms Distribution Characteristics Research of Compensated Hepatitis Liver Cirrhosis Group with Prolonged Prothrombin Time

目的:通过临床流行病学调查,分析探讨凝血酶原时间延长的代偿期肝炎肝硬化患者症状分布特点。方法:收集符合选择标准的代偿期肝炎肝硬化患者,采集其一般资料、症状(一般症状、舌象、脉象)和凝血酶原时间(PT)的结果。录入数据后,运用SPSS 20.0统计软件对数据进行卡方检验,比较各个症状在PT延长患者与未延长患者之间的频率。结果:代偿期肝炎肝硬化患者中,PT延长组与PT未延长组患者相比,浮肿、目涩、腹胀、纳呆、厌油腻、便溏、尿量减少在PT延长组频率高于PT未延长组频率,且有统计学意义(P<0.05)。结论:PT延长的代偿期肝炎肝硬化患者中,浮肿、尿量减少、腹胀、纳呆、厌油腻、便溏、目涩出现频率较高,说明PT延长可能与脾气虚、水湿内停、阴虚有关。

Objective： To conduct a clinical epidemiological study so as to explorate symptoms distribution characteristics of compensated hepatitis liver cirrhosis group with prolonged prothrombin time. Methods： The cases suffering from compensated hepatitis liver cirrhosis were selected and their general information,symptoms（ general symptoms,tongue-apperance and pulse manifestation） and prothrombin time were recorded. Data analysis was used by SPSS 20. 0 and chi-squared test was used to compare the frequency of each symptom between group with prolonged prothrombin time and group without prolonged prothrombin time. Results： The frequency of edema,dry eye,abdominal distension,anorexia,anaerobic greasy,loose stool and oliguria was statistically higher in group with prolonged prothrombin time（ P〈0. 05）. Conclusion： The appearance frequency of edema,oliguria,abdominal distension,anorexia,anaerobic greasy,loose stool and dry eye is higher in the group suffering from compensated hepatitis liver cirrhosis with prolonged prothrombin time. This shows that the extension of PT may be connected with spleen Qi deficiency,water and dampness retention and yin deficiency.