分析比较经皮冷冻消融术与微波消融术治疗肝癌的可行性和安全性

Comparison of percutaneous cryoablation and microwave ablation for hepatocellular carcinoma:easibility and safety

目的分析比较经皮冷冻消融术与微波消融术治疗肝癌的可行性和安全性。方法选取我院2010年3月~2014年5月共62例肝癌患者作为研究对象,根据治疗方式的不同,分为观察组和对照组各31例。对照组采用经皮冷冻消融术进行治疗,观察组采用微波消融术进行治疗,对比两组患者的临床疗效。结果两组患者近期疗效比较,差异无统计学意义(P>0.05)。观察组患者远期疗效优于对照组患者,差异有统计学意义(P<0.05)。观察组患者并发症发生率低于对照组患者,差异有统计学意义(P<0.05)。结论经皮冷冻消融术与微波消融术治疗肝癌均具有一定的临床疗效,可行性较高,其中冷冻消融术的安全性更高,并发症发生率更低,值得在临床推广应用。

Objective To compare the feasibility and safety of percutaneous cryoablation with microwave ablation for hepatocellular carcinoma （HCC）. Methods A total of 62 cases with liver cancer in our hospital from March 2010 to May 2014 were selected as the research objects.According to the different treatment,all cases were divided into the observation group and the control group with 31 cases in each group.The control group was treated with percutaneous cryoablation,and the observation group was treated with microwave ablation treatment.The clinical efficacy between two groups was compared. Results There was no significant difference in short-term efficacy between two groups （P 〉 0.05）,with no statistical significance.The long-term curative effect of the observation group was better than that of the control group,which showed significant difference （P 〈 0.05）.The complication rate in the observation group was lower than that in the control group,and the difference was significantly different （P 〈 0.05）. Conclusion Percutaneous cryoablation and microwave ablation for hepatocellular carcinoma has certain clinical curative effect,high safety and feasibility.Percutaneous cryoablation shows better safety and feasibility,with lower complication rate,worthy of clinical application.