浙江省天台县发热伴血小板减少综合征流行特征及隐性感染状况调查

Epidemiological characteristics of severe fever with thrombocytopenia syndrome and its inapparent infection in Tiantai County,Zhejiang Province

目的了解浙江省天台县发热伴血小板减少综合征发病特点及流行特征。方法采用主动监测和病例流行病学调查,采集监测对象及病例血清学标本,用荧光定量PCR方法进行检测;以描述性流行病学的方法对2012-2015年天台县发热伴血小板减少综合征病例及相关监测数据进行分析。结果 2012-2015年,天台县共报告发热伴血小板减少综合征病例12例,死亡2例;其中男性5例,女性7例;发病最小年龄39岁,最大年龄75岁;发病高峰在4-8月份;蜱虫叮咬史有8例(67%)。临床表现主要为发热(100%)、畏寒和乏力(83%)、全身酸痛(75%);重点地区无症状人群新型布尼亚病毒核酸监测阳性率1.4%。结论天台县已发现多例发热伴血小板减少综合征病例,而且从无症状人群中检测到新型布尼亚病毒核酸,应加强发热伴血小板减少综合征病例监测、防控及健康教育工作。

We investigated the characteristics and epidemiological characteristics of severe fever with thrombocytopenia syn drome （SFTS） infection in Tiantai County, Zhejiang Province. Active surveillance and epidemiological investigation were em ployed with the serum samples collected simultaneously. The samples were detected by fluorescence quantitative PCR assay recommended by national standard of China. By descriptive epidemiology, the SFTS cases in 2012-2015 in Tiantai and related data were analyzed. In 2012 2015, there were 12 new cases of SFTS infection and 2 deaths, including 5 males and 7 females （39 to 75 yrs）. The peak incidence was found from April to August. The main clinical manifestations was fever （100 % ）, chills and fatigue （83%）, and body pain （75%）. The positive rate of nucleic acid screened in subclinical population was 1.4% ; 8 ca ses with definite records of tick bites （670%）. In conclusion, several cases of SFTS have been confirmed in Tiantai County with two inapparent infections, which suggest the urgency and importance to strengthen the active surveillance, prevention and con- trol measures and health education s in the coming days.