摘要
动态血液病表现为血液细胞的数量出现大范围的波动,其主要病因是造血干细胞数量的异常变化.本文针对四阶造血系统,针对于临床上表现为动态血液病的血细胞数量变化的振荡模式,通过造血系统的双参数分岔分析表明:当一个参数发生变化而导致系统出现振荡解时,可以通过调整另外一个参数将振荡解转化为稳定的平衡解,从而维持病人的血细胞数量的稳定.
Dynamic blood disease appears in a wide range of fluctuations on the number of blood cells, which is primarily abnormal changing in the hematopoietic stem cell number. In a fourth order hematopoietic system, a changing parameter leads to different oscillation modes of the number of blood cells in the dynamic blood disease. oscillations Through two-parameter bifurcation analysis on the hematopoietic system, we can push a oscillatory mode into a stable equilibrium state by adjusting another parameter to maintain the stability of the number of blood cells.
作者
赵松
杨卓琴
Zhao Song Yang Zhuoqin(School of Mathematics and Systems Science and LMIB, Beihang University, Beijing 100191, China)
出处
《动力学与控制学报》
2017年第5期472-475,共4页
Journal of Dynamics and Control
基金
国家自然科学基金项目(11372013)
中央高校基本科研业务费专项资金资助~~
关键词
造血系统
分岔
动态血液病
振荡解
稳定平衡解
hematopoiesis, bifurcation, dynamical blood disease, oscillations, stable steady state
