两种贴膜对PICC置管病人局部皮肤过敏影响的Meta分析

Influence of two kinds of sticking film on local skin allergy in patients undergoing PICC catheterization:Meta-analysis

[目的]对PICC置管病人应用IV3000透明敷料与3M透明贴膜局部皮肤过敏文献进行Meta分析。[方法]计算机检索Cochrane Database of Systematic Reviews、JBI Database of Systematic Review、PubMed、中国生物医学文献数据库、万方数据库和中国知网数据库。查阅相关PICC置管病人应用IV3000透明敷料与3M透明贴膜局部皮肤过敏的随机对照试验(RCT)。[结果]共纳入6项RCT,Meta分析的结果显示:IV3000透明敷料与3M透明贴膜相比,局部皮肤过敏发生率差异有统计学意义[OR=0.14,95%CI(0.08,0.25),P<0.05]。[结论]IV3000贴膜比3M透明贴膜能更好地预防PICC置管病人的局部皮肤过敏,提高病人的舒适度。

Objective：To evaluate local skin allergy status of applying IV3000 transparent dressing and 3M transparent dressing to PICC catheterization patients by Meta-analysis. Methods： Such databases as Cochrane Database of systematic reviews,JBI database of systematic review, PubMed, Chinese biomedical literature database, Wanfang database and CNKI database were electronically searched to collect randomized controlled trials （RTCs） on comparison on local skin allergy status of using IV3000 transparent dressing and 3M transparent film in PICC patients. Results： Six RCTs studies were included totally. Meta-analysis showed that： between IV3000 transparent dressing and 3M transparent film,the incidence of local skin allergy was statistically significant different[OR=0.14,95%CI（0. 08,0.25）, P〈0.05]. Conclusion： IV3000 film was better than 3M transparent film in efficacy of preventing skin allergy in PICC patients and improving degree of comfort for patients.