超声造影在甲状腺结节良恶性鉴别诊断中的价值

Value of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant thyroid nodules

目的探讨超声造影在鉴别甲状腺良、恶性结节中的应用价值。方法对96例甲状腺结节患者共152个结节术前行超声造影检查,观察其超声造影增强模式特征,并与病理结果进行对照分析。结果术后病理结果,良性结节75个,恶性结节77个。良性结节超声造影主要表现为等增强或高增强、无增强及环状增强(64/75),多呈均匀性增强(43/75);恶性结节超声造影主要表现为早期低增强或低增强,无环绕增强(70/77),多呈不均匀增强(74/77)。超声造影的增强强度、增强模式、有无环绕增强,在甲状腺良恶性结节鉴别中具有显著相关性,差异有统计学意义(P<0.01)。结论超声造影在甲状腺结节良恶性鉴别诊断中能提供更多有效的诊断信息。

Objective To investigate the value of contrast-enhanced ultrasonography in differentiating benign and malignant thyroid nodules. Methods A total of 152 nodules in 96 patients with thyroid nodules were examined by contrast-enhanced ultrasound,and the contrast enhanced mode features of the nodules were observed and compared with the pathological results. Results Postoperative pathological results included 75 benign nodules and 77 malignant nodules. Benign nodular contrast-enhanced ultrasonography showed enhanced or enhanced enhancement,no enhancement and annular enhancement（64/75）,mostly homogeneous enhancement（43/75）;Malignant nodules were mainly characterized by early low enhancement or low enhancement,no surround enhancement（70/77）,mostly non-uniform enhancement（74/77）. The enhanced intensity,enhancement mode and surround enhancement of CEUS have significant correlation in the differentiation of benign and malignant thyroid nodules,and the difference is statistically significant（P〈0.01）. Conclusion CEUS can provide more effective diagnostic information for the differential diagnosis of benign and malignant thyroid nodules.