北京某社区中老年人群代谢综合征与干眼症的相关性研究

The correlation between metabolic syndrome and dry eye syndrome in middle-aged and elderly community-dwelling residents in Beijing

目的分析中老年人群代谢综合征(Met S)与干眼症(DES)患病风险的相关性。方法以北京海淀区会城门社区40岁及以上的1738名常住居民作为研究对象,采取干眼问卷调查并完成Met S相关人体指标测量、相关实验室及裂隙灯检查。结果 Met S患病率为32%,DES患病率为24.7%,其中女性患病率均高于男性(P<0.05)。Logistic回归分析显示,在校正年龄、吸烟饮酒状态及教育水平后,Met S各组分中,高血糖和高三酰甘油是DES的患病的独立危险因素。结论北京市中老年人群中Met S和DES患病具有相关性,其中,高血糖和三酰甘油是DES患病的危险因素。

Objective To analyze the pathogenic correlation between metabolic syndrome （MetS） and dry eye syndrome （DES）. Methods 1738 adults age 40 or older from Huichengmen Community of Haidian District, Beijing were involved to complete DES questionnaires combined with laboratory tests, anthropometric measures and slit-lamp examinations. Results Morbidities of MetS and DES was 32% and 24.7% respectively. The incidences in female patients were significantly higher than those in male （P 〈 0.05）. Logistic regression analysis indicated that hyperglycemia and hyperlipidemia were independent risk factors for MetS after correcting ages, smoking, drinking and education level. Conclusion Positive correlation was observed between MetS and DES. Hyperglycemia and hyperlipidemia were the independent risk factors for MetS.