中风发病机制的肝源说

Hypothesis of liver dysfunction-caused stroke

我国脑卒中的发病率已经超过心肌梗死和肿瘤,成为居民第一大死亡原因。近20年来虽然投入巨资,但是其发病率不降反升。究其原因,中风发病的源头因素仍值得探索,治疗缺乏整体框架。针对脑卒中的核心病理变化——动脉粥样硬化的成因,中医认为卒中与心、肝、肾三脏之络的平衡失调关系密切,肝失濡养,殃及心脑,因而笔者推导出中风发病机制的肝源说。据此,可以引出心脑血管病治疗和预防的新策略,从源头上狙击中风的高发势头,具有一定的理论价值和潜在的临床应用前景。

Surpassing myocardial infarction and cancer, stroke has been the leading cause of death in China. In the past 20 years, the incidence of stroke did not fall in spite of huge amounts of money invested. The reasons are the unclear pathogenesis of stroke and the lack of overall framework of treatment. According to the core pathological changes of atherosclerosis, that is, abnormal blood lipids and bilirubin abnormality, traditional Chinese medicine holds that stroke is closely related with the balance disorders among the heart, liver and kidney. Therefore, we proposed that the onset of stroke may be caused by the liver losing nutrition leading to the injury of the brain. Based on the hypothesis of liver dysfunctioncaused stroke, we made a new strategy for the prevention and treatment of stroke--controlling stroke from the source. The hypothesis has certain theoretical value and prospect of clinical application.