丝裂霉素联合可调整缝线小梁切除术治疗青光眼的临床效果观察

Clinical Effect Observation of Mitomycin Combined with Adjustable Suture Trabeculectomy in the Treatment of Glaucoma

目的探讨丝裂霉素联合可调整缝线小梁切除术治疗青光眼的临床效果.方法在医院 2 0 1 4年 1 2 月- 2 0 1 5年 6 月期间诊治的青光眼患者中抽取 7 9例作研究对象并随机分成观察组 （ n = 40）、对照组 （ n = 3 9 ） ,前者应用丝裂霉素联合可调 整缝线小梁切除术方案,后者单纯实施常规小梁切除术,就2组治疗效果与并发症发生率进行统计学软件分析.结①观 察组治疗总有效率是 97. 5% ,高于对照组的 84. 6%（P〈0. 0 5 ） ;②观察组并发症发生率是 2. 5% ,与对照组的 17. 9%相比有 明显的统计学差异（ P〈0. 05）.结论青光眼采取丝裂霉素联合可调整缝线小梁切除术治疗方案,可降低患者并发症发生 率,安全有效,可将其作为青光眼患者首选治疗方案.

Objective To investigate the clinical effect of mitomycin combined with adjustable suture trabeculectomy in the treatment of glaucoma. Methods A total of 79 glaucoma patients admitted to our hospital from December 2014 to June 2015 were enrolled in the study. The patients were randomly divided into observation group （n = 40） and control group （n =39）. The former was treated with mitomycin and adjustable suture trabeculectomy program, the latter simply received the conventional trabeculectomy alone, the effect of treatment and the incidence of complications in two groups were analyzed by statistical software. Results ？ The total effective rate was 97. 5% in the observation group, which was higher than 84. 6% of the control group （P〈0 . 05）. ？ The complication rate was 2. 5% in the observation group and 17. 9% in the control group, the difference was statistically significant（P〈0. 05）. Conclusion The combination of mitomycin and djustable suture trabecu-lectomy in glaucoma can reduce the incidence of complications, it is safe and effective, and can be employed as the prior treat-ment of glaucoma patients.