摘要
目的对比分析神经外科手术高血压患者分别采用静吸复合麻醉以及全身静脉麻醉处理对患者血浆高敏 C 反应 蛋白 （hs - CRP）和应激反应造成的影响.方泫选取本院64例神经外科手术高血压患者分为 I 组（采用静吸复合麻醉方式）和 II组（采用全身静脉麻醉方式）,分别记手术前、手术中、手术后2h、术 后 24 l i为丁0、丁1、丁2、丁3,并且测定两组患者各时点 血浆 hs -CRP、白细胞以及血糖等各项指标情况.结果 I 组、 II组患者 T0、 T1、 T2 各时点 hs-CRP水平有-定下降,但 是 T3 时点均显著升高（ P〈 0 . 0 5 ）,而且 I 组患者 T3时点 lis-CRP水平高于 II组（ P〈 0 . 0 5 h 两组患者 T0-T3 各时点血糖、白细 胞计数均有逐渐升高的趋势,但是两组各时点指标并没有明显区别（ P〉0. 05h 结论神经外科手术高血压患者采用全身静 脉麻醉处理相对于静吸复合麻醉而言,术后 lis-CRP水平下降会更明显（ P〈0. 05）,而且也不会增加患者术后应激反应,更 值得推广 .
Objective To compare the effects of intravenous inhalation anesthesia with systemic intravenous anesthesia on plasma high-sensitivity C-reactive protein （hs-CRP） and stress response in hypertension patients underwent neurosurger-y. Methods 64 hypertension patients received neurosurgery in our hospital were divided into two groups： group I （with intra-venous inhalation anesthesia） and group II （systemic intravenous anesthesia）. Preoperatively, intraoperatively, 2h postopera-tively and 24h postoperatively results were recorded as TO, T1, T2 and T3 , respectively. The plasma level of hs-CRP, white blood cells？ blood glucose and other indicators at every time point in both group were determined. The levels of hs-CRP in group I and II decreased at TO, T1 and T2 , but increased significantly at T3 （P〈C〇 . 05） , and the level of hs-CRP in group I of T3 was significantly higher than that in group II （P〈C〇 . 05）. The blood glucose and white blood cell count of T0-T3 gradually increased in both groups, but no significant difference was shown between the two groups （P^〉 0. 05）. Conclusion When compared with the hypertension patients underwent neurosurgery received intravenous inhalation anesthesia, the level of hs-CRP of the patients received systematic intravenous anesthesia decreased significantly （P〈C0. 05） ？ and it did not increase the postoperative stress response, which is more worthy of promotion.
出处
《临床研究》
2017年第9期59-60,共2页
Clinical Research
