摘要
目的探讨^(125)I粒子植入术在小细胞肺癌治疗的安全性及疗效。方法随访分析经细胞学或病理学检查确诊为小细胞肺癌并在CT引导下进行^(125)I粒子植入术治疗的27例患者,根据随访情况进行近期疗效、客观缓解率、无疾病进展生存期、中位生存期等指标的观察及统计。结果 27例患者行^(125)I粒子植入术后出现气胸1例,咯血1例,无粒子移位、栓塞等其他并发症。术后随访1、3、6个月的客观缓解率分别为74%、74%、59%,无疾病进展生存期为10.25个月,中位生存期为15.50个月。结论 CT引导下^(125)I粒子植入术是安全、微创的方法,可以作为小细胞肺癌患者的一种治疗选择。
Objective To investigate the safety and efficacy of ^125I seed implantation in small cell lung cancer.Methods CT-guided radioactive ^125I seed implantation therapy was performed in 27 patients with small cell lung cancer diagnosed by cytological or pathological examination.The short-term effect,objective response rate,progression-free survival time and median survival time were observed and analyzed.Results Among the 27 patients,1 had pneumothorax and 1 had hemoptysis after ^125I seed implantation.No seed translocation,embolism and other complications occurred in all patients.The objective response rates were 74%,74%and 59% after follow-up for 1,3 and 6 months,respectively.The progression-free survival time and median survival time were 10.25 and 15.50 months,respectively.Conclusion CT-guided radioactive ^125I seed implantation is a safe and minimally invasive treatment for small cell lung cancer.
出处
《实用临床医学（江西）》
CAS
2017年第8期6-8,17,108,共5页
Practical Clinical Medicine
关键词
^125I
放射性粒子植入
小细胞肺癌
疗效判定
^125I
radioactive seed implantation
small cell lung cancer
therapeutic effect analysis
