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超滤浓缩脑脊液ESAT-6对结核性脑膜炎的诊断价值 被引量:1

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摘要 目的探讨离心超滤技术浓缩脑脊液检查结核杆菌早期分泌性抗原靶蛋白6(ESAT-6)在诊断结核性脑膜炎(TBM)中的价值。方法选取TBM患者40例(TBM组)和非TBM患者20例(非TBM组),每位患者留取2份脑脊液(一份为原液,另一份为离心超滤浓缩),使用ELlSA法检测其ESAT-6水平。结果 TBM组中浓缩ESAT-6的敏感性高于原液(P<0.05),而非TBM组中浓缩ESAT-6的敏感性与原液比较差异无统计学意义(P>0.05)。结论利用离心超滤浓缩技术能提高脑脊液ESAT-6检查的敏感性,且操作简单,可作为快速诊断TBM的参照指标。
出处 《实用临床医学(江西)》 CAS 2017年第8期25-26,28,共3页 Practical Clinical Medicine
基金 江西省卫计委科技计划(20165076)
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