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长期应用质子泵抑制剂致低镁血症的临床分析 被引量:9

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摘要 目的观察长期应用质子泵抑制剂导致低镁血症的临床发生情况。方法选取长期应用质子泵抑制剂患者108例为研究对象,按照质子泵抑制剂应用时间分为A组(3个月内)、B组(3~12个月)、C组(12个月以上),每组36例。观察3组患者低镁血症发生率、治疗前后血镁值比较。结果 C组低镁血症发生率高于A组、B组,差异有统计学意义(P<0.05或P<0.01)。B组、A组低镁血症发生率差异无统计学意义(P>0.05)。治疗前,C组血镁值高于A组和B组(P<0.05)。A组、B组治疗前血镁值差异无统计学意义(P>0.05)。治疗后,C组血镁值低于A组、B组(P<0.05)。结论长期应用质子泵抑制剂时需密切监测血镁浓度,以便早期发现、早期诊断、早期治疗低镁血症,避免严重低镁血症的发生。
出处 《临床合理用药杂志》 2017年第26期95-96,共2页 Chinese Journal of Clinical Rational Drug Use
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