血清孕酮、β-HCG联合检测在早期先兆流产中的诊断价值

Diagnostic Value of Combined Detection of Serum Progesterone and β-HCG in Early Threatened Abortion

目的讨论血清孕酮、β-HCG联合检测在早期先兆流产中的诊断价值。方法病例均方便选自2015年6月—2016年6月期间,实验组选取该院救治的先兆流产的患者32例,对照组选取在该院救治的流产的患者44例,健康对照组选取健康的志愿者30名,3组均实行血清孕酮、β-HCG的检测,对3组的检测结果实行比较。结果对照组患者的血清孕酮、β-HCG分别为(11.5±6.8)ng/m L、(4 531.1±436.3)m IU/m L检测低于健康对照组(25.9±8.7)ng/m L、(18325.2±551.3)m IU/m L,实验组(16.6±6.5)ng/m L、(13 452.5±441.7)m IU/m L,差异有统计学意义(P<0.05)。血清孕酮,β-HCG以及血清孕酮联合β-HCG的特异性为86.00%,100.00%,91.00%。结论可以使用血清孕酮、β-HCG联合检测早期的先兆流产,从而提高对患者出现先兆流产的预测,具有重要的临床价值。

Objective This paper tries to discuss the combined detection of serum progesterone and β-HCG in the early diagnosis of threatened abortion. Methods 23 patients with threatened abortion in this hospital from June 2015 to June 2016 were convenient selected as the experimental group. 44 cases of abortion cured in this hospital were selected as the control group, and 30 healthy volunteers were selected as the healthy control group. The serum progesterone and β-HCG were detected in the three groups. The results of the three groups were compared. Results Serum progesterone and β-HCG were（11.5±6.8） ng/m L and（4531.1±436.3） m IU/m L in the control group, lower than that in the healthy control group of（25.9±8.7）ng/m L（18 325.2±551.3）m IU/m L, and the experimental group of（16.6 ±6.5）ng/m L and（13 452.5±441.7）m IU/m L, the differences were statistically significant（P〈0.05）. The specificity of serum progesterone, β-HCG and serum progesterone combined withβ-HCG were 86.00%, 100.00% and 91.00% respectively. Conclusion Serum progesterone and β-HCG can be used to detect early threatened abortion, so as to improve the prediction of threatened abortion in patients, which has important clinical value.