XAD-16大孔树脂对恩拉霉素的吸附热力学和动力学性质研究

Adsorption Thermodynamics and Kinetics of Enramycin on XAD-16 Macroporous Resin

目的研究恩拉霉素在XAD-16大孔树脂上吸附的动力学和热力学特性。方法通过静态吸附实验,利用实验数据对相关等温模型进行拟合来描述XAD-16大孔树脂对恩拉霉素的等温吸附行为;用热力学参数对恩拉霉素吸附过程的热力学性质进行描述;分别采用准一级动力学方程和准二级动力学方程探讨XAD-16大孔树脂吸附恩拉霉素的动力学特性。结果在298~308 K内,Freundlich模型能较好的描述XAD-16大孔树脂对恩拉霉素的吸附等温过程;ΔH<0,ΔG<0,恩拉霉素在XAD-16大孔树脂上的吸附属于自发的物理吸附过程;XAD-16大孔树脂对恩拉霉素吸附过程符合准二级动力学方程。结论通过对恩拉霉素在XAD-16大孔树脂上吸附热力学和动力学的研究,为XAD-16大孔树脂大规模分离纯化恩拉霉素提供了理论依据。

OBJECTIVE To investigate the adsorption thermodynamics and kinetics of enramycin on XAD - 16 macroporous resin. METHODS Series of static adsorption experiments were carried out. The adsorption equilibrium data were fitted to Langmuir and Freundlich isotherm equations, which could describe the adsorption behavior of enramycin on XAD - 16 macroporous resin. The ther-modynamic properties were described by thermodynamic parameters. Then, pseudo-first-order model and pseudo-second-order model were applied to describe the kinetics of adsorption process. RESULTS The adsorption equilibrium data were agreed with Langmuir i- sotherm well. Thermodynamic analysis suggested/tH 〈 0, and AG 〈 0, which indicated the adsortion procedure was a spontaneously exothermic reaction with entropy decrease. The adsorption of enramycin on XAD - 16 macroporous resin could be described well by Pseu- do-second-order model. CONCLUSION The adsorption thermodynamics and kinetics of enramycin on XAD - 16 macroporous resin can supply the theory for the separation and purification of enramycin on XAD - 16 macroporous resin.