黄芪注射液联合血塞通注射液对冠心病患者心功能的影响

Effect of astragalus injection and Xuesaitong injection on cardiac function in patients with coronary heart disease

目的探讨黄芪注射液联合血塞通注射液对冠心病患者心功能的影响。方法选择我科收治的90例冠心病患者,随机分为试验组及对照组,各45例。两组患者均给予西药常规治疗,观察组在此基础上加用静脉滴注黄芪注射液联合血塞通注射液。比较两组患者治疗前、后左室舒张末期容积(EDV)、左室收缩末期容积(ESV)、左室射血分数(LVEF)及治疗效果。结果治疗前,两组患者的EDV、ESV、LVEF比较,差异无统计学意义(P>0.05);治疗后,两组间患者的EDV、ESV和LVEF均优于治疗前,且观察组优于对照组(P<0.05)。观察组患者的治疗总有效率为86.67%,明显高于对照组的68.89%(P<0.05)。结论在常规治疗的基础上予以黄芪注射液联合血塞通注射液能明显改善冠心病患者的心功能,减少EDV、ESV和升高LVEF,从而改善患者的预后。

Objective To investigate the effect of astragalus injection and Xuesaitong injection on cardiac function in patients with coronary heart disease （CHD）. Methods Ninety cases of patients with CHD admitted in our department were select- ed and randomly divided into experimental group and control group, with 45 cases in each group. The two groups were given conventional western medicine, while the observation group added astragalus injection and Xuesaitong injection. The Left ven- tricular end-diastolic volume （EDV）, left ventricular end - systolic volume （ESV）, left ventricular ejection fraction （LVEF） before and after treatment, and therapeutic effects were compared between the two groups. Results Before treatment, there were no significant differences in EDV, ESV and LVEF between the two groups （PM）.05）; after treatment, the EDV, ESV and LVEF of the two groups were superior to those before treatment, and those of the observation group were superior to the control group （P〈0.05）. The total effective rate of the observation group was 86.67%, which was significantly higher than 68.89% of the control group （P〈 0.05）. Conclusion On the basis of routine treatment, astragalus injection combined with Xuesaitong injection can significantly improve cardiac function in patients with CHD, reduce EDV, ESV and increase LVEF, so as to improve the prognosis of patients.