Co^(2+)/Dy^(3+)掺杂纳米立方Fe_3O_4的热还原制备及磁靶向滞留性能

Thermal Reduation Preparation of Co^(2+)/Dy^(3+)Doped Cubic Fe_3O_4 and Their Magnetic Targeting Retention

采用热还原沉淀法制备了一系列Co^(2+)/Dy^(3+)掺杂的纳米立方MxFe3-xO4磁性颗粒.利用X射线衍射仪、透射电子显微镜和振动样品磁强计研究了不同含量掺杂离子对MxFe3-xO4晶体结构、形貌及磁性的影响.研究发现,掺杂未改变母体的对称性,但母体形貌逐渐从立方体向球体过渡;Co^(2+)和Dy^(3+)的掺杂对于铁氧体磁学性质的影响明显不同,当Co^(2+)实际掺杂量为0.44和Dy^(3+)实际掺杂量为0.05时,MxFe3-xO4立方磁性粒子的饱和磁化强度(Ms)达到最大值,分别为76.65和70.21 A·m2·kg-1.与超顺磁性Fe_3O_4球体相比,高磁性掺杂Fe_3O_4立方体在体外模拟磁流体磁靶向定位实验中显示出较高的滞留率.

Co^（2＋）/Dy^（3＋）doped Fe_3O_4nanoparticles（ MxFe3-xO4） were synthesized by the thermal reduction and co-precipitation methods. The structure,morphology and magnetic properties of MxFe3-xO4 were characterized by means of X-ray diffractometer（ XRD）,transmission electron microscope（ TEM） and vibrating sample magnetometer（ VSM）. The results show that the dopants did not change the maternal symmetry,and the maternal morphology gradually transformed from cube to sphere. The MxFe3-xO4 cubic magnetic particles have maximum saturation magnetization of 76. 65 and 70. 21 A · m2· kg-1,respectively,when Co^（2＋）actual doping amount is equal to 0. 44 and Dy^（3＋）actual doping amount is equal to 0. 05. Compared with the superparamagnetic Fe_3O_4,the cubic high magnetic doped Fe_3O_4 nanoparticles showed a high retention rate in the simulated magnetic fluid magnetic targeting experiment in vitro.