针刺治疗结石性肾绞痛Meta分析

Acupuncture Therapy for Calculous Renal Colic:A Meta Analysis

目的:系统评价针刺治疗结石性肾绞痛的临床疗效。方法:计算机检索中国知识资源总库、中国生物医学文献数据库、维普数据库,收集针刺治疗结石性肾绞痛的随机对照临床试验或半随机对照临床试验,检索时限均从建库至2016年,对纳入研究的方法学质量进行评价,用RevMan5.3软件进行统计分析。结果:最终纳入14篇研究文献,共1 357例患者。Meta分析结果显示:与对照组比较,针刺治疗结石性肾绞痛在总有效率[OR=6.88,95%CI(4.19,11.28),P<0.05]、起效时间[MD=-9.37,95%CI(-11.77,-6.97),P<0.05]、不良反应[OR=0.04,95%CI(0.01,0.14),P<0.05]等方面均优于西药治疗组,差异具有统计学意义(P<0.05)。发表性偏倚分析提示纳入研究文献可能存在潜在发表偏倚。结论:针刺治疗结石性肾绞痛具有疗效确切、起效快、安全性高及副作用小的优点,但仍需更多临床研究进一步证实。

Objective：To evaluate the clinical efficacy of Acupuncture in the treatment of calculous renal colic. Methods：Retrieved from China Knowledge Resources, Chinese Biomdical literature Database and Wanfang Database, randomized or quasirandomized controlled trials about Acupuncture in the treatment of calculous renal colic were collected, the evaluated by the methodological quality, statistical analyzed with RevMen 5.3 software. Results： 14 studies involving 1357 patients entered the inclusion criteria. Compared with the control group,the results of meta analysis showed that Acupuncture therapy for calculous renal colic in the total effective rate[OR=6.88,95;CI（4.19,11.28）,P〈0.05],onset time[MD= - 9.37,95;/0CI（- 11.77,-6. 97）,P〈0. 05],and the side effect[OR = 0.04,95 ; CI （0.01,0.14）, P〈0.05], the difference was statistically significant. ＇Funnel Plot＇ bias analysis indicate that there may be a potential publication bias. Conclusion ： Acupuncture therapy for calculous renal colic with exact effect rapid onset, high safety and light side effects, But still need more clinical research to further verify.