测定儿茶酚胺对手足口病的临床意义

Clinical significance of catecholamine determination in hand-foot-mouth disease

目的对儿茶酚胺测定在手足口病的意义进行临床研究分析,为今后的临床诊疗工作提供有价值的参考信息。方法选择2014年1月至2016年6月间,我院儿科收治的手足口病患儿50例,将其按照诊疗指南分成普通组(n=25)、重型组两组(n=25),而后对两组患儿的发病情况进行观察,对儿茶酚胺含量、血压、心率、病原学类型进行检测。结果重型组患儿血液中儿茶酚胺含量较普通组发生明显升高(P<0.05)。重型组患儿的血压、心率异常率明显高于普通组,组间差异有显著性(P<0.05)。结论手足口病患儿的病情严重程度与儿茶酚胺水平存在明显的正相关,患儿交感神经处在兴奋的状态,在发病中发挥了重要作用,今后的诊疗工作中,应对其给予足够的重视。

Objective To analyze the significance of catecholamine in the diagnosis and treatment of band-foot- mouth disease, and to provide valuable reference information for future clinical diagnosis and treatment. Methods Fifty children with hand-foot-mouth disease diagnosed clinically in our hospital from January 2014 to June 2016 were randomly divided into two groups： normal group （n= 25） and severe group （n = 25）. Observed the conditions of disease, and detected the catecholamine content, blood pressure, heart rate, etiological type Results The blood catecholamine content in severe group was significantly higher than those in the normal group （P〈0.05）. The abnormal rates of blood pressure and heart rate in the severe group were higher than those in the normal group （P〈0.05）.Conclusions The severity of hand-foot-mouth disease is positively correlated to catecholamine levels, the sympathetic nerve is in the excited state, plays an important role in the incidence of this disease, and we should give enough attention on it in future treatment work.