摘要
目的探讨桂枝茯苓胶囊联合克林霉素治疗盆腔炎合并盆腔积液的临床疗效及对患者生活质量的影响。方法纳入2014年1月至2016年12月我院收治的72例盆腔炎合并盆腔积液患者作为研究对象,随机分为两组各36例。对照组采用克林霉素治疗,观察组在此基础上加用桂枝茯苓胶囊治疗。比较两组患者的临床疗效,观察两组治疗前后的世界卫生组织生活质量测定量表(WHOQOL-BREF)评分变化。结果 Ridit分析结果表明,对照组R=0.586,95%置信区间=(0.493,0.678),观察组R=0.414,95%置信区间=(0.337,0.492),两组无可重复区间,差异具有统计学意义(P<0.05)。治疗前两组患者的健康状况、日常活动、自我感觉、生存质量得分及总分比较无统计学差异(P>0.05),治疗后两组患者的上述指标较治疗前显著升高(P<0.05),且观察组的各项得分及总分均显著高于对照组(P<0.05)。结论采用桂枝茯苓胶囊联合克林霉素治疗盆腔炎合并盆腔积液患者具有显著的临床疗效,可有效提高患者的生活质量。
Objective To explore the clinical effect of Guizhi Fuling capsule combined with clindamycin in the treatment of pelvic inflammation complicated with pelvic effusion and its impact on patients' quality of life. Methods 72 cases of patients with pelvic inflammation complicated with pelvic effusion admitted to our hospital from January 2014 to December 2016 were selected as research objects. All cases were randomly divided into two groups, with 36 cases in each group. The control group was treated with clindamycin, while the observation group was treated with Guizhi Fuling capsule combined with clindamycin. The clinical effects of two groups were compared, and the changes of scores of WHOQOL-BREF before and after treatment were observed. Results Ridit analysis showed that the R value and 95% confidence interval were 0.586 and (0.493, 0.678) in control group, and 0.414 and (0.337,0.492) in observation group, respectively; No repeatable interval was found in two groups, and the difference was statistically significant (P 〈0.05). Before treatment, no statistical difference was found between two groups in the total score of WHOQOL-BREF, and scores of health status, daily activities, self perception and quality of life (P〉0.05); After treatment, both groups had significantly increased WHOQOL-BREF scores (P〈0.05), and the total score of WHOQOL-BREF and scores of each factors of WHOQOL-BREF of observation group were significantly higher than those of control group (P 〈0.05). Conclusions Guizhi Fuling capsule combined with clindamycin in the treatment of pelvic inflammation complicated with pelvic effusion has significant clinical curative effect; Also, it can improve patients' quality of life effectively.
出处
《临床医学工程》
2017年第10期1419-1420,共2页
Clinical Medicine & Engineering
关键词
桂枝茯苓胶囊
克林霉素
盆腔炎
盆腔积液
生活质量
Guizhi Fuling capsule
Clindamycin
Pelvic inflammation
Pelvic effusion
Quality of life