血清同型半胱氨酸、乳酸脱氢酶对急性胰腺炎预后的影响

Influence of Serum Homocysteine and Lactate Dehydrogenase on the Prognosis of Acute Pancreatitis

目的探讨血清同型半胱氨酸(HCY)、乳酸脱氢酶(LDH)对急性胰腺炎患者预后的影响。方法选取2015年1月至2017年6月我院收治的急性胰腺炎患者96例为研究对象,根据病情严重程度分为轻型组(52例)和重型组(44例),观察比较两组患者入院后各时间段的血清同型半胱氨酸和乳酸脱氢酶水平。结果入院后第1 d、5 d、7 d、14 d,重型组的HCY、LDH水平均显著高于轻型组,差异有统计学意义(P<0.05)。结论血清同型半胱氨酸、乳酸脱氢酶均能提示急性胰腺炎的严重程度,同时可作为预后评估的重要指标。

Objective To explore the influence of serum homocysteine and lactate dehydrogenase on the prognosis of acute pancreatitis. Methods 96 cases of patients with acute pancreatitis admitted to our hospital from January 2015 to June 2017 were selected as research objects. According to the severity of disease, all cases were divided into mild group （52 cases） and severe group （44 cases）. At different time points after admission, the levels of serum homocysteine and lactate dehydrogenase of two groups were observed and compared. Results At 1 d, 5 d, 7 d, 14 d after admission, the levels of serum homocysteine and lactate dehydrogenase of severe group were significantly higher than those of mild group, with statistical differences （P 〈0.05）. Conclusions Serum homocysteine and lactate dehydrogenase can indicate the severity of acute pancreatitis, and can be used as important indicators for prognosis evaluation.