摘要
In the past two decades, extensive studies have focused on a group of so-called polarity proteins that play conserved and essential functions in establishing and maintaining cell polarity in epithelial cells. Among them, Crumbs （Crb） is the only trans- membrane polarity protein characterized to date （Tepass et al.,
In the past two decades, extensive studies have focused on a group of so-called polarity proteins that play conserved and essential functions in establishing and maintaining cell polarity in epithelial cells. Among them, Crumbs （Crb） is the only trans- membrane polarity protein characterized to date （Tepass et al.,
基金
supported by the grants from the National Institutes of Health of USA(NCRR R21RR024869, NIGMS RO1GM086423 and RO1GM121534 to Y.H.)
the Start-up Foundation from Nanjing Medical University (2012RC04 to J.H.)
University of Pittsburgh Medical School Center for Biologic Imaging was supported by the grant 1S100D019973-01 from NIH, USA
