鼻咽癌发生与ABO血型分布的相关性研究

Study on association between the distribution of ABO blood type and nasopharyngeal carcinoma

目的探究鼻咽癌的发生与ABO血型是否存在联系。方法将1 136例在中山大学肿瘤防治中心确诊为鼻咽癌并进行血型鉴定的患者纳入研究(鼻咽癌组),对鼻咽癌组与广州中医药大学第一附属医院2013年健康体检人群(对照组)的血型分布进行比较。结果鼻咽癌组与对照组之间的血型分布差异没有统计学意义(P=0.884),鼻咽癌组不同分期之间的血型分布差异也没有统计学意义(P=0.506)。结论 ABO血型与南方人群当中鼻咽癌的发生、鼻咽癌的分期尚无关联。

Objective To investigate possible association between the incidence of nasopharyngeal carcinoma（NPC）and ABO blood type.Methods pathologically confirmed NPC patients（NPC group）with a serologically determined blood group in Sun Yatsen University Cancer Center were reviewed retrospectively.The distribution of blood groups of the NPC group were compared with the distribution of blood groups of healthy donors（control group）admitted to the First Affiliated Hospital of Guangzhou TCM University in the year 2013.Results There was no significant difference between NPC group and the control group in terms of distribution of ABO blood groups（P=0.884）,neither with NPC stages（P=0.506）.Conclusion In this study,we found that blood type has no association with an increased risk of NPC and NPC stages in a population of Southern China.