综合护理干预对腹腔镜胃癌根治术患者术后胃肠功能及胃肠激素的影响

Effect of comprehensive nursing intervention on postoperative gastrointestinal function and gastrointestinal hormones in the patients undergoing laparoscopic radical gastrectomy of lung cancer

目的观察综合护理干预对腹腔镜胃癌根治术患者术后胃肠功能及胃肠激素的影响。方法将2014年1月~2016年1月我院行腹腔镜胃癌根治术的患者90例作为研究对象,根据护理方法不同所有患者随机分为观察组和对照组。对照组在临床治疗过程中实施常规护理,观察组行综合性护理干预措施,比较两组患者术后肠鸣音恢复时间、首次肛门排气时间、首次肛门排便时间及两组患者治疗前后胃泌素(GAS)水平、胃动素(motilin,MTL)水平、血管活性肠肽水平(vasoactive intestinal peptide,VIP)的变化情况。结果观察组患者的肠鸣音恢复时间、首次肛门排气时间、首次肛门排便时间分别为(21.24±10.18)h、(26.12±5.16)h、(50.34±8.14)h,分别显著短于对照组,组间比较存在显著差异(P<0.05),观察组患者治疗后的胃泌素(GAS)水平、胃动素(motilin,MTL)水平分别为(131.1±23.2)ng/L、(167.4±25.0)ng/L,分别显著低于对照组,血管活性肠肽水平(vasoactive intestinal peptide,VIP)为(295.7±35.8)ng/L,显著高于对照组,组间比较存在显著差异(P<0.05)。结论对腹腔镜胃癌根治术患者采取综合护理干预,可以促进患者胃肠功能的恢复,考虑可能与手术与护理对胃肠激素的调节作用有关。

Objective To observe the effect of comprehensive nursing intervention on postoperative gastrointestinal function and gastrointestinal hormones in the patients undergoing laparoscopic radical gastrectomy of lung cancer.Methods A total of 90 patients undergoing laparoscopic radical gastrectomy of lung cancer in our hospital from January 2014 to January 2016 were selected as the research subjects. All the patients were randomly divided into observation group and control group according to different nursing methods. The control group was given routine nursing care during the course of clinical treatment, and the observation group was given comprehensive nursing intervention measures.The time of bowel sounds recovery, the time of first anal exhaust, the first anal defecation time after the surgery, as well as the changes of the levels of gastrin(GAS), motilin(MTL) and vasoactive intestinal peptide(VIP) before and after the treatment were compared between the two groups. Results The recovery time of bowel sounds, the time of first anal exhaust and the first anal defecation were(21.24 ±10.18) h,(26.12±5.16) h and(50.34 ±8.14) h respectively in the obser vation group, which were significantly shorter than those in the control group, and there were significant differences between the two groups(P <0.05). The levels of gastrin(GAS) and motilin(MTL) in the observation group were(131.1 ±23.2) ng/L and(167.4 ±25.00 ng/L after the treatment, which were significantly lower than those in the control group.The level of vasoactive intestinal peptide(VIP) was(295.7±35.8) ng/L, which was significantly higher than that in the control group. All the differences between groups were significant(P<0.05). Conclusion Comprehensive nursing intervention for the patients undergoing laparoscopic radical gastrectomy of lung cancer can promote the recovery of gastrointestinal function, which is considered to be related to the regulation of gastrointestinal hormones by surgery and nursing.