呋塞米与托拉塞米对慢性心力衰竭的治疗有效性对比研究

A Comparative Study on the Efficacy of Furosemide and Torasemide in the Treatment of Chronic Heart Failure

目的:比较呋塞米与托拉塞米治疗慢性心力衰竭的临床效果。方法:选择某院48例慢性心力衰竭患者随机分为观察组和对照组各24例,对照组给予呋塞米治疗,观察组给予托拉塞米治疗。结果:观察组和对照组各24例,观察组总有效率为95.83%,对照组为75.00%,观察组有效率明显高于对照组(P<0.05);治疗后,观察组血钠、血钾水平低于对照组,尿量高于对照组,差异均有统计学意义(P<0.05);观察组不良反应发生率为0.00%,对照组为16.67%,观察组显著低于对照组(P<0.05)。结论:托拉塞米治疗慢性心力衰竭起效快,不良反应小,较呋塞米有更好的治疗效果。

Objective：To compare the clinical effect of furosemide and torasemide in the treatment of chronic heart failure.Methods：A total of 48 patients with chronic heart failure were randomly divided into observation group and control group.The control group was treated with furosemide and the observation group was treated with torasemide.Results：The effective rate was 95.83% in the observation group and 75.00% in the control group,with statistically significant difference（P〈0.05）.After treatment,the levels of serum sodium and serum potassium in the observation group were lower than those in the control group,and the urine volume was higher than that of the control group（P〈0.05）.The incidence of adverse reactions was 0.00% in the observation group and 16.67% in the control group,and the observation group was lower than the control group（P〈0.05）.Conclusion：The effect of Torasemide in the treatment of chronic heart failure is rapid with small adverse reactions,which is better than the effect of furosemide.