腹膜后脂肪肉瘤复发转移及预后的探讨

Study of recurrence,metastasis and prognosis of primary retroperitoneal liposarcoma.

目的 探讨原发性腹膜后脂肪肉瘤复发、转移机理及预后。方法 复习原发性腹膜后脂肪肉瘤临床资料及文献 ,总结伴有亚型转化的原发性腹膜后脂肪肉瘤病人的生存时间及复发率。分析反复复发与远处转移的关系。结果 伴有亚型转化的病人平均复发次数高于非亚型转化病人 ,但生存时间较长。肿瘤复发可诱导去分化危险。结论 亚型转化使腹膜后脂肪肉瘤的复发次数增加而不影响生存期。肿瘤复发诱导去分化危险 ,肿瘤可获得转移的能力。

Objective To study the mechanism of recurrence and metastasis of primary retroperitoneal liposarcoma and its prognosis. Methods To review the clinical information and references,and compare the recurrence rate and the survival time of the patients with subtype exchanging and the patients without subtype exchanging.To analyze the relation between recurrence and metastases.Results The recurrence rate of the patients with subtype exchanging was higher than that of the patients without subtype exchanging,but the forme lived longer.The recurrence of sarcoma could induce the dedifferentialed danger.Conclusion The subtype exchanging in the patients who suffered from the primary retroperitoneal liposarcoma can increase the recurrence rate.The ability of metastases to other organs is increased in dedifferentiated retroperitoneal liposarcoma.