大承气汤联合复方聚乙二醇电解质散用于肠道准备的临床研究

Dachengqi Decoction Granule Combined with Compound Polyethylene Glycol Electrolyte Powder in Intestinal Preparation

目的探讨大承气汤配方颗粒联合复方聚乙二醇电解质散用于肠道准备中的临床作用。方法将150例志愿者随机分成5组各30例,分别给与大承气汤配方颗粒(A组)、甘露醇(B组)、硫酸镁(C组)、复方聚乙二醇电解质散(D组)、大承气汤配方颗粒+复方聚乙二醇电解质散(E组)治疗。观察肠道清洁度及不适反应。结果在肠道清洁度方面,E组分别优于A组、B组、C组比较,差异具有统计学意义(均P<0.05),与D组比较,差异无统计学意义(P>0.05);在不适反应方面,E组的不良反应较A组、B组、C组、D组少,差异具有统计学意义(均P<0.05)。结论大承气汤配方颗粒联合复方聚乙二醇电解质散的肠道清洁效果好,不适反应小,患者依从性好。

Objective To study the clinical effect of Dachengqi decoction gran ule combined with compound polyethylene glycol electrolyte powder in intestinal preparation. Methods A total of 150 volunteers were randomly divided into five groups： Dachengqi decoction（ group A）, Mannitol（ group B）, Magnesium Sulfate（ group C）, compound polyethylene glycol electrolyte powder（group D）, Dachengqi decoction granule and compound polyethylene glycol electrolyte powder（group E） 5 groups. The intestinal cleanliness and adverse reactions were observed. Results In the intestinal cleansing, group E was better than group A, group B and group C, and the difference was statistically significant（ χ2= 25.45, P 〈0.05）. Comparing with group D, there was statistically significant（ χ2= 0.27, P〉 0.05）. In adverse reactions, adverse reactions in group E were lower than those in group B, group A,group C and group D, and the difference was statistically significant（ χ2= 16.70, P 〈0.05）. Conclusion Dachengqi decoction granule combined with compound polyethylene glycol electrolyte power has good intestinal cleaning effect, less adverse reaction and good patient compliance.