摘要
MicroRNA(miRNA)是一类内源性、非编码蛋白质的短链RNA。近年来,大量研究报道了一些miRNAs在人类癌症中的异常改变,参与癌的形成、浸润以及转移过程,已经迅速发展为食管癌等癌症的重要生物标记物。文章综述了近几年miRNA在食管癌的诊断、治疗及预后的研究进展。
MicroRNAs (miRNA) are endogenous small and noncoding RNAs. In recent years, a great many studies have shown that there is a high correlation exists between abnoralal expression of miRNAs and cancer's occurrence, differentiation, metastasis and recurrence, therefore miRNA is expected to be a biomarker of esophageal cancer. The article reviews the research progress of miRNA in the diagnosis, treatment and prognosis of esophageal cancer recently.
出处
《黑龙江医学》
2017年第9期912-913,共2页
Heilongjiang Medical Journal
基金
四川省教育厅课题(14ZA0200)
四川省卫生计生委科研课题(130345)
关键词
MIRNA
食管癌
诊断
治疗
预后
MicroRNA
Esophageal cancer
Diagnosis
Treatment
Prognosis