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γδT细胞淋巴瘤一例并文献复习

γδTT-cell lymphoma: report of one case and review of literature
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摘要 目的探讨γδT细胞淋巴瘤的临床特点和诊疗方法,提高对γδT细胞淋巴瘤的认知和诊疗水平。方法回顾性分析1例γδT细胞淋巴瘤患者的临床特点及治疗情况并复习相关文献。结果患者经hyperCVAD-A(环磷酰胺+吡柔比星+长春新碱+地塞米松)、hyperCVAD-B(甲氨蝶呤+阿糖胞苷)方案化疗后,病情一过性好转,后病情进行性加重,出现骨髓转移,最终临床死亡,生存时间4个月。结论非肝脾来源的γδT细胞淋巴瘤是一种罕见的高度侵袭性肿瘤,病情进展快,预后差,主要通过组织病理学、免疫组织化学及克隆性T细胞抗原受体γ和(或)δ基因重排诊断,早期诊断,尽早行造血干细胞移植有望改善患者预后。
作者 张晓婷 邱志远 冉学红 Zhang Xiaoting Qiu Zhiyuan Ran Xuehong(Department of Hematology, Weifang People' s Hospital, Weifang 261000, China)
出处 《白血病.淋巴瘤》 CAS 2017年第9期549-552,共4页 Journal of Leukemia & Lymphoma
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