间苯三酚联合地屈孕酮治疗胚胎移植术后先兆流产的疗效分析

Treatment of threatened abortion by phloroglucinol combined with dydrogesterone in the embryo transfer

目的探讨间苯三酚联合地屈孕酮治疗胚胎移植术后先兆流产的临床效果。方法选择本所自2015年5月至2015年9月收治符合条件的胚胎移植术后先兆流产患者86例,随机分为观察组和对照组,观察组采用间苯三酚联合地屈孕酮治疗,对照组使用地屈孕酮治疗,统计2组先兆流产患者症状缓解及消失时间、孕酮水平、继续妊娠率以及药物不良反应。结果观察组患者的症状缓解及消失时间较对照组缩短;治疗后,2组血孕酮水平较治疗前显著增高,观察组增高程度更明显;观察组继续妊娠率明显高于对照组;观察组药物不良反应发生率较对照组低(P<0.05)。结论间苯三酚联合地屈孕酮治疗胚胎移植术后先兆流产疗效显著,继续妊娠率高,药物不良反应少,适宜临床推广使用。

Objective To analyze of the efficacy of phloroglucinol combined with dydrogesterone in the treatment of threatened abortion after embryo transfer. Methods Totally 86 patients after embryo transfer with threatened abortion in our hospital from May to September 2015 were randomly divided into an observation group and a control group, the observation group was treated with phloroglucinol combined with dydrogesterone, while the control group was treated with dydrogesterone. The symptom relief of the two groups of threatened abortion patients and the disappearance time, progesterone levels, continue pregnancy rate and adverse drug reactions were summarized. Results The symptom relief and disappearance time of the observation group was shorter than that of the control group. After the treatment, the blood progesterone levels in both groups were significantly higher than before the treatment, and the observation group incresed more obviously. The continued pregnancy rate of the observation group was significantly higher than that of the control group. The incidence of drug adverse reactions in the observation group was lower than that in the control group （P 〈 0.05）. Conclusion Phloroglucinol combined with dydrogesterone in the treatment of threatened abortion after embryo transfer is effective, with high pregnancy rate, and few adverse drug reactions.