悬铃木花粉微颗粒(SPPs)释放的快速有效观察

Rapid and Effective Observation of Subpollen Particles(SPPs) Released from Platanus Pollen

悬铃木的风媒花粉是春季主要的上呼吸道过敏病症的诱发因素之一。已被鉴定出的致敏原蛋白包括Pla a1(Platanus allergen 1)、Pla a2和Pla a3三种。和其他花粉蛋白一样,悬铃木花粉变应原蛋白能够吸附于细颗粒物上,并通过呼吸道进入人体而引发过敏反应。但是,对于悬铃木花粉细胞内部的这些致敏原蛋白的释放方式和过程却缺乏相应的细致观测和研究。因此,该研究主要通过建立快速简便的检测方法和分析不同处理方式对悬铃木花粉中内容物释放的影响,以确定悬铃木花粉致敏原的释放方式和条件,为花粉过敏机制的相关研究积累数据。

Platanus hispanica anemophilous pollen is one of the important factors inducing upper respiratory allergic diseases in the spring. The Pla a1（Platanus allergen 1）, Pla a2 and Pla a3 are three main allergen proteins, which have been identified in Patanus. Like other pollen proteins, Platanus pollen allergen can cause allergic effects, by adhereing to the fine particles and entering the body through the respiratory tract. But there is a lack of detailed observation and research on the mode and pathway of release of allergens in the interior of the pollen grains. This research mainly established rapid and simple detection method, and analyzed the influence of different treatments on the release of the contents from pollen grains. Furthermore, it would determine the method and condition of Platanus pollen allergen release and accumulate date for the study of pollen allergy mechanisms.