配伍活血化瘀理气类中草药在治疗冠心病心绞痛患者中的应用

Clinical Analysis: Herbal Medicine of Activating Blood,Removing Stasis and Regulating Qi in Coronary Heart Disease and Angina Pectoris

目的:探讨活血化瘀理气类中草药配伍治疗冠心病心绞痛的治疗效果与方法。方法:将2015年2月至2016年2月心血管内科与中医科会诊治疗冠心病心绞痛患者中随机抽80例分为观察组和对照组,每组40例;对照组患者用单硝酸异山梨酯缓释片+富马酸比索洛尔片进行治疗,观察组用活血化瘀理气类中草药口服治疗。结果:经过1个月治疗后,观察组的治疗总有效率为87.5%,对照组的治疗总有效率为70%,差异有统计学意义(P<0.05);对照组经过治疗后,共有6例患者出现了不良反应,其中眩晕头痛2例,低血压1例,胃肠道反应2例,皮疹1例,不良反应发生率为15%。观察组经过治疗后有3例患者出现了不良反应,其中皮肤过敏1例,胃肠道反应2例,不良反应发生率为7.5%,差异均有有统计学意义(P<0.05)。结论:应用活血化瘀理气类中草药配伍治疗冠心病心绞痛可以显著改善患者的体征和临床症状,降低患者心绞痛的发作次数和持续时间,具有较好的临床治疗效果。

Objective： To investigate the effect and method of herbal medicine of activating blood,removing stasis and regulating qi in the treatment of coronary heart disease and angina pectoris; Methods： There are 80 patients who were suffering from coronary heart disease and angina pectoris and were in our hospital from February 2015 to February 2016 being selected,and they were divided into an observation group and a control group,with 40 cases in each. The control group of patients were treated with single nitrate isosorbide esters sustained-release tablets and fumarate bisoprolol tablets,the observation group herbal medicine of activating blood,removing stasis and regulating qi. Results： After 1 month of treatment,the total efficiency of treatment of the observation group was 87. 5%,the control group 70%,with statistical significance（ P 〈 0. 05）. After treatment,there were 6 cases of patients having adverse reactions in the control group,including 2 cases of dizziness and headache,1 case of hypotension,2 cases of gastrointestinal reaction and 1 case of skin rash,and the adverse reactions occurring rate was 15%. After treatment,there were 3 cases of patients with adverse reactions,1 case of skin allergy,2 cases of gastrointestinal reaction and the adverse reactions occurring rate was 7. 5%,besides,the differences were statistically significant（ P 〈 0. 05）. Conclusion： The application of herbal medicine of activating blood,removing stasis and regulating qi in the treatment of coronary heart disease and angina pectoris can significantly improve the patients’ the clinical symptoms and signs,reduce angina attack frequency and duration,with a better clinical therapeutic effect.