老年冠心病患者经桡动脉入路行冠状动脉介入治疗的可行性和安全性

Feasibility and Safety of Transradial Approach for Coronary Intervention in the Elderly Patients with Coronary Artery Disease

目的观察和分析老年冠心病患者经桡动脉入路行冠状动脉介入治疗的可行性和安全性。方法选取112例行经皮冠状动脉介入治疗（PCI）的老年冠心病患者作为研究对象，将其随机分为观察组和对照组，每组各56例，对照组患者采用经股动脉入路行PCI术，观察组患者采用经桡动脉入路行PCI术。对两组患者的手术情况、术后血管并发症发生率进行观察和比较；对两组患者进行为期1年的随访，比较两组患者术后的严重心脏不良事件发生率。结果观察组患者的住院时间、住院费用均显著低于对照组，两组之间的差异均有统计学意义（P〈0．05）。观察组患者术后血管并发症的总发生率和局部血肿的发生率均显著低于对照组，两组之间的差异均有统计学意义（P〈0．05）。观察组患者随访期内严重心脏不良事件总发生率显著低于对照组，两组之间的差异有统计学意义（P〈0．05）。结论采用经桡动脉入路PCI治疗老年性冠心病能够促进患者的康复、降低术后血管并发症发生率、改善患者的预后。

Objective To observe and analyze the feasibility and safety of transradial approach for coronary intervention in the elderly patients with coronary artery disease. Methods 112 Elderly patients with coronary heart diseases underwent percutaneous coronary intervention （PCI） were selected and randomly divided into the observation group （n = 56） and the control group （n = 56）. The control group received PCI treatment by femoral approach and the observation group accepted PCI treatment by transradial approach. The perioperative indexes and the incidences of postoperative vascular complication in the two groups were observed and compared. The patients in the two groups were followed up for 1 year and the incidence of postoperative serious adverse cardiac events in the two groups were compared. Results The hospitalization time and the hospitalization costs in the observation group were significantly lower than those in the control group. There were statistically significant difference between the two groups （P 〈 0. 05）. The overall incidence rate of postoperative vascular complications and local hematoma in the observation group was significantly lower than that in the control group. There were statistically significant difference between the two groups （ P 〈 0. 05 ）. The overall incidence rate of postoperative serious adverse cardiac events during the follow - up period in the observation group was significantly lower than that in the control group. There was statistically significant difference between the two groups （ P 〈 0. 05 ）. Conclusion Transradial approach for PCI can treat coronary heart disease in the elderly patients effectively, which can promote the rehabilitation, reduce the incidence of postoperative vascular complications and improve the prognosis of these patients.