稳定期COPD患者深吸气量与运动耐力的关系

Predictive value of inspiratory capacity to exercise capacity in patients with stable chronic obstructive pulmonary disease

目的探讨深吸气量（IC）及相关肺功能指标与稳定期中重度COPD患者运动耐力的相关性。方法对62例处于稳定期的中重度COPD患者进行常规肺功能检测及斜坡式功率递增症状限制性心肺运动试验，测定相关肺通气功能参数、气体交换参数。结果COPD患者的IC％pred与运动耐力[峰值摄氧量占预计值的百分比（peak0Oz％pred）]有显著的相关性（r=0．74，P〈0．001），IC％pred对peak VO2％pred有显著预测意义。结论IC％pred对稳定期COPD患者运动耐力的预测较其他肺功能指标更有优势。

Objective To evaluate the relationship of the exercise capacity in patients with stable moderate to severe chronic obstructive pulmonary disease（COPD） with the lung function tests, especially the inspiratory capacity（IC）.Methods Pulmonary lung function test（PFT） and cardiopulmonary exercise test（CPET） were tested in 62 patients with stable moderate to severe COPD and 30 controls, and measured the parameters of ventilation and gas exchange. Results IC% pred was significant associated with exercise capacity（ r=.74, P d0. 001）in COPD, it has significant validity of the prediction to peak V2%red. Conclusions IC%red provides the efficient information to estimate the exercise capacity in patients with stable COPD, and its predictive value is better than other parameters.