摘要
根据异质二聚体构成肽链的不同，T淋巴细胞可分为αβT细胞和γδT细胞。不同于αβT细胞，γδT细胞具有独特的基因组成、表面标志、分布特点、抗原识别机制、免疫学功能及生物学意义。目前支气管哮喘（简称哮喘）的气道一免疫炎症机制得到大多数学者公认。γδT细胞数量虽少，但在哮喘免疫炎症机制中发挥重要作用。本文就帕T细胞分布、基因特点、免疫功能以及在哮喘的作用机制进行综述。
According to different peptide chains forming heterodimer, T lymphocytes can be divided into αβT cells and γδT cells. Unlike αβT cells, γδT cells have unique genetic constitution, surface markers, distribution characteristics, antigen recognition mechanism, immunological function and biological significance. At the present time the mechanism of airway-immune inflammation in bronchial asthma （asthma） has been recognized by most scholars. Although γδT cells are of small amounts, they play an important role in the mechanism of immune inflammation in asthma. This article reviews the distribution, genetic characteristics, immunological functions of γδT cells as well as the mechanisms in asthma.
作者
陈丽丹
李超乾
Chen Lidan Li Chaoqian(Department of Respiratory Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China)
出处
《国际呼吸杂志》
2017年第19期1489-1493,共5页
International Journal of Respiration
基金
国家自然科学基金（81470230）
