洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎的疗效观察

Curative Effect on Allergic Rhinitis of Nasal Washing with Mometasone Furoate and Loratadine

目的:观察洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎的临床疗效。方法:选取庆阳市人民医院门诊收治的100名过敏性鼻炎患者依据不同的治疗方案随机分为对照组和观察组,坚持治疗8周,分析两组患者的总体疗效及鼻炎症状评分、不良反应发生率和停药后3个月内的复发率。结果:观察组总有效率高于对照组,两者比较差异有统计学意义(P<0.05);观察组鼻炎症状及TNSS评分低于对照组,差异有统计学意义(P<0.05);2组药物不良反应比较,差异无统计学意义(P>0.05);停药后,观察组过敏性鼻炎复发率低于对照组,两者比较差异有统计学意义(P<0.05)。结论:洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎,可以有效改善患者鼻炎症状,总体疗效高且复发率低,值得临床推广。

Objective： To observe clinical effects of allergic rhinitis treated with nasal washing with mo- metasone furoate and loratadine. Method ： collect 100 cases of allergic rhinitis in Qingyang municipal hos- pital＇ s outpatient department, which were divided randomly into control group and observation group ac- cording to different planning treatments. Hold the treatment in 8 weeks, and then analyze sufferers in 2 groups about general efficacy, symptom score, the ADR rate and recurrence rate in following 3 mouths. Re- sult： Effective rate in control group is higher than observation group, comparative difference has statistical significance （ P 〈 0.05 ） ; Symptom score and TNSS in control group is lower, and the difference has signif- icance （P 〈 0.05 ） ;The ADR rate in 2 has no significance （P 〉 0.05 ） ;After treatment, recurrence rate in control group is lower, and the difference has significance（ P 〈 0.05 ）. Conclusion ： This treatment has ef- fective improvement for allergic rhinitis sufferers. The general efficacy is higher with lower recurrence which deserves clinical expansion.