留置导尿管截瘫患者尿路感染病原菌分布及耐药性分析

Distribution and drug resistance of pathogens causing urinary tract infection in patients with indwelling catheter

目的了解留置导尿管截瘫患者尿路感染的常见病原菌分布及耐药情况。方法收集我院2014年1月—2016年12月225例(留置导尿管60例,非留置导尿管165例)截瘫伴尿路感染者尿标本,进行病原学检测和药敏试验。结果共分离出病原菌241株,其中留置导尿管组72株,大肠埃希菌占43.0%,白色假丝酵母菌占11.1%,非留置导尿管组169株,其中大肠埃希菌占59.8%,并呈多重耐药性,留置导尿管组细菌耐药率高于非留置导尿管组。结论加强病原菌培养和耐药性检测,对指导临床合理使用抗生素具有重要意义。

Objective： To understand the distribution and drug-resistance of common pathogens in urinary tract infection in paraplegia patients with indwelling catheter,and to provide theoretical foundation for reasonable application of antibacterial agents in clinics. Methods： 225 cases of urine specimens from paraplegia patients with urinary tract infection were collected in our hospital from January 2014 to December 2016（ including 60 cases with indwelling catheter and 165 without indwelling catheter） for etiological detection and drug sensitive test. Results： Altogether 241 strains of pathogens were isolated,including72 from indwelling catheter group and 169 from non-indwelling catheter group. Pathogens in indwelling catheter group were Escherichia coli（ 43. 0%）,fungus（ 11. 1%）,pathogen in non-indwelling catheter group was Escherichia coli（ 59. 8%）,and ther multi-drug resistance was found. Drug-resistance rate of pathogens to antibacterial agents in indwelling catheter group was higher than that in non-indwelling catheter group. Conclusion： It is of great significance to guide the clinical rational use of antibiotics in order to strengthen the culture of pathogenic bacteria and drug resistance.